பிரிட்டிஷ் ஜர்னல் ஆஃப் ரிசர்ச் திறந்த அணுகல்

சுருக்கம்

Bone substitute biomaterials

Marwa OUERGHEMMI

Bioceramics are used in several biomedical applications, particularly in reconstructive surgery, either as replacement elements or bone substitutes (scaffolds). These implants must have a high porosity rate to facilitate the delivery of nutrients and allow a high cell penetration. Although their biological function can be ensured in this way, their mechanical properties will be compromised due to the large amount of void volume It is therefore essential to maintain their mechanical strength as well as possible and to evaluate their service life in order to guarantee their integrity until the new bone regeneration of tissues.In this context of my graduation thesis, my goal was to develop porous bioceramics by the polymeric sponge method and understand the influence of the porosity and its distribution on the mechanical behavior through numerical and experimental studies.