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Sugar-Based Biopolymers: Biologically Active Poly(Sugar Acid) – Poly[3-(3,4-Dihydroxyphenyl)Glyceric Acid] from Medicinal Plants of Boraginaceae Family

Vakhtang Barbakadze

Novel representative of sugar-based biopolymers is the main chemical constit¬uent of high molecular (>1000 kDa)
water-soluble preparations from medicinal plants of Symphytum asperum, S. caucasicum, S. officinale, S. grandiflorum,
Anchusa italica, Cynoglossum officinale and Borago officinalis (Boraginaceae). According to data of liquid-state 1H,
13C NMR, 2D 1H/13C HSQC, 2D DOSY and solid-state 13C NMR spectra this biopolymer was found to be poly[oxy-
1-carboxy-2-(3,4-dihydroxyphenyl)ethylene] or poly[3-(3,4-dihydroxy¬phenyl)glyceric acid] (PDPGA) with the
3-(3,4-dihydroxyphenyl)glyceric acid residue as the repeating unit. The polyoxyethylene chain is the backbone of this
polymer molecule and 3,4-dihydroxyphenyl and carboxyl groups are regular substituents at two carbon atoms in the
chain. PDPGA as 3,4-dihydroxyphenyl derivative of poly(2,3-glyceric acid ether) belongs to a rare class of poly(sugar
acids) as well. Poly(2,3-glyceric acid ether) chain is the backbone of this polymer and 3,4-dihydroxyphenyl groups are
regular substituents at carbon atoms in the chain. .