Abhilasha Tiwari, Guy Moeneclaey, Graham Jenkin and Mark A Kirkland
Hematopoietic stem cells (HSCs) are responsible for maintenance and production of functional blood cells. Each day the human body produces billions of new white blood cells, red blood cells, and platelets to replace blood cells lost to normal cell turnover processes as well as to illness or trauma. The highly orchestrated process of blood cell production and homeostasis is termed hematopoiesis. HSCs circulate around the blood during fetal stage and reside in the bone marrow of adults.
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